Huang Y, Zhang S, Zou P, et al.
Abstract Background. To investigate the antenatal diagnosis of a pregnant fetus after intracytoplasmic sperm injection (ICSI) and blastocyst transplantation. By integrating multiple technologies, we clarified the specific characteristics of the 20p mosaic duplication, evaluated i…
Su K, Wen K, Chen L, et al.
Abstract Background: High-grade serous ovarian carcinoma (HGSOC) is the most lethal subtype of ovarian cancer and is increasingly recognized to originate from serous tubal intraepithelial carcinoma (STIC) in the fallopian tube epithelium. DNA methylation alterations occur early i…
Ng J, Trannguyen J, Wilkinson R, et al.
Abstract Clostridioides difficile is a highly methylated organism within the gut microbiome that is responsible for Clostridioides difficile infection (CDI), a common disease that is mediated by toxins production from the bacterium. C. difficile infection is ten times more common…
Huang Y, Luo S, Qi Y, et al.
Abstract Background: As the only survivable sex chromosome monosomy, Turner syndrome (TS) demonstrates a certain association with cardiovascular disease (CVD), which severely impacts patients' quality of life. While the CVD phenotype and prognosis differ among TS patients suffe…
Li Z, Liu J, Hong J, et al.
Abstract Background Azacitidine (AZA) is a hypomethylating agent with well-known antileukemic activity. The addition of AZA to intermediate-dose Cytarabine (IDAra-c) plus idarubicin (Ida) or etoposide (Eto) in consolidation may improve outcomes in acute myeloid leukemia (AML) pat…
Mareckova K, Pelant L, Marecek R, et al.
Abstract Premature epigenetic aging has been linked to poorer cognitive performance, but the neuroanatomical pathways underlying this association remain unclear. Therefore, we tested whether premature epigenetic aging predicts deviations from normative brain development and cogni…
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